The main research interest of our lab is to elucidate the underlying molecular and cellular mechanisms of genetic psychiatric disorders such as psychomotor retardation, Fragile X syndrome (FXS), and sleep disturbances.

 

To understand these brain deficiencies, we combine the use of genetic manipulations, real-time 2-photon imaging of single organelles, synapses and neurons, and video-tracking of behavior in live zebrafish. The zebrafish is a simple transparent vertebrate with conserved organization of the central nervous system. Furthermore, it is ideally suited for genetic manipulation and high-resolution imaging of the entire brain in a live animal.

 

We develop zebrafish models for human brain disorders. The function of genes and neuronal circuits is determined using loss-of-function (CRISPR-mediated genome editing as well as genetic silencing and ablation of a specific neuronal population) and gain-of-function (transposon-mediated transgenesis) experiments.

 

Our general goal is to link gene function with the development and plasticity of neuronal circuits that regulate specific behavior.

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Next to the fish system 6

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Lior
Lior

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Brain bow.jpg
Brain bow.jpg

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Next to the fish system 6

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Dr. Tali Levitas-Djerbi
Dr. Tali Levitas-Djerbi

Alumna Phd.Student

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Dr. Adi Shamay
Dr. Adi Shamay

Alumna Phd. Student

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Inbal Adnati
Inbal Adnati

Alumna MSc. Student

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Ricarina Rabinovitz
Ricarina Rabinovitz

MSc

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Dr. Einat Blitz
Dr. Einat Blitz

Alumna Postdoctoral Fellow Email: einat.blitz@gmail.com

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Dr. Adi Tovin
Dr. Adi Tovin

Alumna Postdoctoral Fellow Email: aditovin@gmail.com

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Dr. Idan Elbaz
Dr. Idan Elbaz

Alumnus Ph.D. student Email: idanelbaz99@yahoo.com

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Dr. Laura Yelin-Bekerman
Dr. Laura Yelin-Bekerman

Alumna Ph.D. student Email: bekerman.laura@gmail.com

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Arnon Itiel
Arnon Itiel

Alumnus M.Sc. student Email: arnonetl@gmail.com

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