The main research interest of our lab is to elucidate the underlying molecular and cellular mechanisms of genetic psychiatric disorders such as psychomotor retardation, Fragile X syndrome (FXS), and sleep disturbances.

 

To understand these brain deficiencies, we combine the use of genetic manipulations, real-time 2-photon imaging of single organelles, synapses and neurons, and video-tracking of behavior in live zebrafish. The zebrafish is a simple transparent vertebrate with conserved organization of the central nervous system. Furthermore, it is ideally suited for genetic manipulation and high-resolution imaging of the entire brain in a live animal.

 

We develop zebrafish models for human brain disorders. The function of genes and neuronal circuits is determined using loss-of-function (CRISPR-mediated genome editing as well as genetic silencing and ablation of a specific neuronal population) and gain-of-function (transposon-mediated transgenesis) experiments.

 

Our general goal is to link gene function with the development and plasticity of neuronal circuits that regulate specific behavior.

Next to the fish system 6
Next to the fish system 6

Lior
Lior

Brain bow.jpg
Brain bow.jpg

Next to the fish system 6
Next to the fish system 6

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Dr. Tali Levitas-Djerbi
Dr. Tali Levitas-Djerbi

Alumna Phd.Student

Dr. Adi Shamay
Dr. Adi Shamay

Alumna Phd. Student

Inbal Adnati
Inbal Adnati

Alumna MSc. Student

Ricarina Rabinovitz
Ricarina Rabinovitz

MSc

Dr. Einat Blitz
Dr. Einat Blitz

Alumna Postdoctoral Fellow Email: einat.blitz@gmail.com

Dr. Adi Tovin
Dr. Adi Tovin

Alumna Postdoctoral Fellow Email: aditovin@gmail.com

Dr. Idan Elbaz
Dr. Idan Elbaz

Alumnus Ph.D. student Email: idanelbaz99@yahoo.com

Dr. Laura Yelin-Bekerman
Dr. Laura Yelin-Bekerman

Alumna Ph.D. student Email: bekerman.laura@gmail.com

Arnon Itiel
Arnon Itiel

Alumnus M.Sc. student Email: arnonetl@gmail.com